MN 553 Pharmacotherapeutics of Gastrointestinal Disorders Essay

For the diagnosis of gastroesophageal reflux disease (GERD), write a prescription for a medication used to treat GERD.

Be sure to indicate drug name, strength, amount per dose, route, frequency of dose, amount to dispense, allow generics, number of refills and any special instruction to the patient

Please, be sure to include the following: 

This assignment involves writing a   prescription for my  patient.

1. Choose a drug that pertains to   the GI tract.

2. Provide information on the   kinetics and dynamics of the drug. 

3. Include what type of   information you would provide to the patient about the drug.

4. Write the prescription. 

Expert Solution Preview

Introduction:

The prescription for treating gastroesophageal reflux disease (GERD) should be based on the individual patient’s symptoms, medical history, and the severity of their condition. The chosen drug should effectively target the underlying causes of GERD, alleviate symptoms, and minimize potential side effects. Furthermore, it is crucial to educate the patient about the medication, its administration, and any additional instructions to ensure optimal treatment outcomes. With these factors in mind, the following prescription is designed to meet the specific needs of a patient with GERD.

1. Drug: Omeprazole
– Omeprazole is a proton pump inhibitor (PPI) that reduces the production of stomach acid. It is commonly used to treat GERD by inhibiting the enzyme responsible for acid secretion in the stomach.

2. Kinetics and Dynamics of Omeprazole:
– Omeprazole is rapidly absorbed from the gastrointestinal tract, with a peak plasma concentration reached within 0.5-3 hours after administration.
– The drug undergoes hepatic metabolism, primarily by the cytochrome P450 system, resulting in the formation of its active metabolites.
– Omeprazole has a half-life of approximately 1-1.5 hours in healthy individuals, but it may be prolonged in patients with liver impairment.
– The therapeutic effects of omeprazole last for approximately 24 hours, which makes once-daily dosing sufficient for most individuals.

3. Patient Information:
– It is important to inform the patient about the purpose, potential side effects, and precautions associated with omeprazole:
– Explain that omeprazole works by reducing the production of stomach acid, which helps relieve symptoms of GERD such as heartburn and acid reflux.
– Discuss possible side effects such as headache, abdominal pain, nausea, and diarrhea. Emphasize the importance of reporting any severe or persistent adverse reactions.
– Advise the patient to take the medication consistently, preferably at the same time each day, to ensure optimal effectiveness.
– Instruct the patient to take omeprazole on an empty stomach, at least 1 hour before meals, for better absorption.
– Reinforce the importance of adopting lifestyle modifications, such as avoiding trigger foods, elevating the head of the bed, and maintaining a healthy weight, for better control of GERD symptoms.

4. Prescription:
– Drug: Omeprazole
– Strength: 20 mg
– Amount per Dose: 1 capsule
– Route: Oral
– Frequency of Dose: Once daily, in the morning
– Amount to Dispense: 30 capsules (for one month’s supply)
– Allow Generics: Yes
– Number of Refills: 3
– Special Instructions: Take omeprazole on an empty stomach at least 1 hour before meals. Report any severe or persistent adverse reactions to your healthcare provider.

By combining adequate pharmacotherapy with patient education, this prescription aims to effectively manage GERD symptoms, improve the patient’s quality of life, and promote long-term control of the disease.

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